Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5657295 | Clinical Gastroenterology and Hepatology | 2017 | 31 Pages |
Abstract
In a retrospective study of patients with lean NAFLD vs obese or overweight persons with NAFLD, we found 20% of patients with lean NAFLD to have NASH, fibrosis scores of 2 or higher, and carotid atherosclerosis. Lean patients with rs738409 C>G in PNPLA3 should be monitored for liver disease progression; studies including large series of patients with lean NAFLD will clarify the possible role of TM6SF2 polymorphisms.
Keywords
CIMTNAFLDWaist sizeNASALTAlanine aminotransferasenonalcoholic steatohepatitisNonalcoholic fatty liver diseaseWaist circumferenceMetabolic syndromebody mass indexBMICarotid intima-media thicknessRisk factorconfidence intervalMETSNonalcoholic fatty liver disease activity scoreNash body weightCarotid plaquesDisease progression
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Authors
Anna Ludovica Fracanzani, Salvatore Petta, Rosa Lombardi, Giuseppina Pisano, Maurizio Russello, Dario Consonni, Vito Di Marco, Calogero Cammà , Laura Mensi, Paola Dongiovanni, Luca Valenti, Antonio Craxì, Silvia Fargion,