Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5657825 | Clinics and Research in Hepatology and Gastroenterology | 2016 | 13 Pages |
Abstract
Dasatinib decreased the inflammation in a rodent model of colitis. It may be provide this effect by the suppression of TNFα. Dasatinib may be one of the treatment options for ulcerative colitis.
Keywords
TNFαMDALarge granular lymphocytosisPDGFRDAIAbelsonSFKCMLIBDMPOSrc family kinasesinterleukinSykCrohn's diseaseInflammatory bowel diseasetumor necrosis factor-alphaTyrosine kinaseSODDentritic cellSuperoxide dismutasedisease activity indexspleen tyrosine kinasenuclear factor kappa betaChronic myeloid leukemiaLglmalondialdehydemyeloperoxidaseplatelet derived growth factor receptorUlcerative colitis
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Authors
Güray Can, Süleyman Ayvaz, Hatice Can, Ä°hsan KaraboÄa, Selim DemirtaÅ, Hasan AkÅit, Bülent Yılmaz, UÄur Korkmaz, Mevlüt Kurt, Turan Karaca,