Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5657844 | Clinics and Research in Hepatology and Gastroenterology | 2017 | 13 Pages |
Abstract
TLR8 expression and function in PBMCs were impaired by chronic HBV infection. Higher TLR8 expression after treatment week 12 could potentially predict complete response to peg-IFN-α-2a therapy.
Keywords
PBMCCHBULNHBsAgHBeAgNCRICSTLRALTMFIAlanine aminotransferaseHepatitis B surface antigeninterferonIFNinterleukintumor necrosis factor αToll-like receptorPeripheral blood mononuclear cellNK cellsConditioned mediumTNF-αmean fluorescence intensityHepatitis B e antigenchronic hepatitis BHBVhepatitis B viruscomplete responsehealthy control
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Authors
Guangying Deng, Jun Ge, Chao Liu, Jinke Pang, Zuxiong Huang, Jie Peng, Jian Sun, Jinlin Hou, Xiaoyong Zhang,