| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5658196 | Gastroenterology | 2016 | 44 Pages |
Abstract
5-HT4R activation maintains motility in healthy colons of mice and guinea pigs, and reduces inflammation in colons of mice with colitis. Agonists might be developed as treatments for patients with inflammatory bowel diseases.
Keywords
5-HTTNBSPBSFITCHDSIJPSRBDSSDAIIBDAFU5-hydroxytryptamine or serotoninTrinitrobenzene sulfonic acidWound HealingInflammatory bowel diseaseColonic motilityanalysis of varianceANOVAGastrointestinaldextran sodium sulfatesulforhodamine Bdisease activity indexfluorescein isothiocyanatePhosphate-buffered salineinhibitory junction potential
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Authors
Stephanie N. Spohn, Francesca Bianco, Rachel B. Scott, Catherine M. Keenan, Alisha A. Linton, Conor H. O'Neill, Elena Bonora, Michael Dicay, Brigitte Lavoie, Rebecca L. Wilcox, Wallace K. MacNaughton, Roberto De Giorgio, Keith A. Sharkey, Gary M. Mawe,