Direct-Acting Antiviral Therapy Restores Immune Tolerance to Patients With Hepatitis C Virus-Induced Cryoglobulinemia Vasculitis

Article ID	Journal	Published Year	Pages	File Type
5658362	Gastroenterology	2017	29 Pages	PDF

Abstract

In a prospective clinical trial of patients with HCV-CV, DAA-based therapy restored disturbances in peripheral B- and T-cell homeostasis.

Keywords

TNF PBMC MFI PDCD1 Br3 VLP DAA Treg TFH EOT Direct-acting antiviral healthy donor interferon IFN interleukin BAFF Post-treatment Liver disease Virus-like particle Regulatory T cell Peripheral blood mononuclear cell tumor necrosis factor Immune regulation mean fluorescence intensity Hepatitis C virus HCV Response to treatment end of treatment

Related Topics

Health Sciences Medicine and Dentistry Gastroenterology

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Direct-Acting Antiviral Therapy Restores Immune Tolerance to Patients With Hepatitis C Virus-Induced Cryoglobulinemia Vasculitis

Authors

Cloé Comarmond, MarlÃ¨ne Garrido, Stanislas Pol, Anne-Claire Desbois, Myrto Costopoulos, Magali Le Garff-Tavernier, Si Nafa Si Ahmed, Laurent Alric, HélÃ¨ne Fontaine, Bertrand Bellier, Anna Maciejewski, Michelle Rosenzwajg, David Klatzmann,