| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5658431 | Gastroenterology | 2017 | 26 Pages |
Abstract
We identified specific genetic and mutation features of HCCs associated with aflatoxin exposure, including mutations in ADGRB1, compared to HCCs from general populations. We associated these mutations with increased vascularization and expression of PD-L1 in HCC tissues. These findings might be used to identify patients with HCC due to aflatoxin exposure, and select therapies.
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Authors
Weilong Zhang, Huan He, Mengya Zang, Qifeng Wu, Hong Zhao, Ling-ling Lu, Peiqing Ma, Hongwei Zheng, Nengjin Wang, Ying Zhang, Siyuan He, Xiaoyan Chen, Zhiyuan Wu, Xiaoyue Wang, Jianqiang Cai, Zhihua Liu, Zongtang Sun, Yi-Xin Zeng, Yuchen Jiao,