| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5658496 | Gastroenterology | 2017 | 79 Pages |
Abstract
MFGE8 is an anti-fibrotic protein in MSC secretomes that strongly inhibits TGFβ signaling and reduces extracellular matrix deposition and liver fibrosis in mice.
Keywords
CCl4MFGE8TIMPsMesenchymal stem/stromal cellUmbilical cord-derived mesenchymal stem cellsHSCsIMDMPEDFUCMSCsTGFECMMSCALBMmpsα-SMAMMPFBSEGFTAAAlbuminIscove’s Modified Dulbecco’s Mediumα-smooth muscle actintransforming growth factorThioacetamidedecorinfetal bovine serumHepatic stellate cellsepidermal growth factorPigment epithelium-derived factorExtracellular matrixMatrix metalloproteinasessecretomeMouse modelTissue inhibitors of metalloproteinasesSignal transductionpolymerase chain reactionPCRCarbon tetrachloride
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Authors
Su Yeon An, Yu Jin Jang, Hee-Joung Lim, Jiyou Han, Jaehun Lee, Gyunggyu Lee, Ji Young Park, Seo-Young Park, Ji Hyang Kim, Byung-Rok Do, Choongseong Han, Hee-Kyung Park, Ok-Hee Kim, Myeong Jun Song, Say-June Kim, Jong-Hoon Kim,