Identification of an Intestinal Microbiota Signature Associated With Severity of Irritable Bowel Syndrome

Article ID	Journal	Published Year	Pages	File Type
5658736	Gastroenterology	2017	65 Pages	PDF

Abstract

In analyzing fecal and mucosal microbiota from patients with IBS and healthy individuals, we identified an intestinal microbiota profile that is associated with the severity of IBS symptoms. Trial registration number: NCT01252550.

Keywords

JSD IBS-M rRNA IBS-SSS FODMAP IBS-D IBS-C AUROC IBS AUC OTU Ribosomal RNA functional bowel disorder hospital anxiety and depression Bacteria Least absolute shrinkage and selection operator HAD Gastrointestinal irritable bowel syndrome with diarrhea irritable bowel syndrome with constipation irritable bowel syndrome body mass index BMI area under the receiver operating characteristic curve area under the curve principal component Microbiome operational taxonomic unit polymerase chain reaction PCR LASSO

Related Topics

Health Sciences Medicine and Dentistry Gastroenterology

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Identification of an Intestinal Microbiota Signature Associated With Severity of Irritable Bowel Syndrome

Authors

Julien Tap, Muriel Derrien, Hans Törnblom, Rémi Brazeilles, Stéphanie Cools-Portier, Joël Doré, Stine Störsrud, Boris Le Nevé, Lena Ãhman, Magnus Simrén,