| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5658928 | Gastroenterology | 2017 | 35 Pages |
Abstract
In a study of mouse and human cell lines, organoids, and tissues, we found cIAP1 to be required for regulation of TNF-induced intestinal epithelial cell death and survival. These findings have important implications for the pathogenesis of TNF-mediated enteropathies and chronic inflammatory diseases of the intestine.
Related Topics
Health Sciences
Medicine and Dentistry
Gastroenterology
Authors
Thomas Grabinger, Konstantin J. Bode, Janine Demgenski, Carina Seitz, M. Eugenia Delgado, Feodora Kostadinova, Cindy Reinhold, Nima Etemadi, Sabine Wilhelm, Matthias Schweinlin, Kay Hänggi, Janin Knop, Christof Hauck, Heike Walles, John Silke,