Article ID Journal Published Year Pages File Type
5663978 Critical Reviews in Oncology/Hematology 2017 9 Pages PDF
Abstract

•Fertility management of patients with malignant ovarian germ cell cancer.•Patients with malignant ovarian germ cell cancer underwent surgical and/or medical treatment.•Tailoring fertility management are need in patients underwent treatment for malignant ovarian germ cell tumor.

Malignant Germ Cell Tumors have primarily affecting adolescents and young adults. In advanced disease, greater than 70% of patients can be cured with standard chemotherapy regimens and fertility-sparing surgery appears to be safe with excellent survival after long-term follow-up.Due to their rarity, follow up and fertility management is largely based on trials of epithelial ovarian cancer or on few small studies.We report a review of the literature studies about the assessment, the monitoring and the treatment of fertility for Malignant Germ Cell Tumors as practical guidelines for management of fertility in these patients.

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