Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5664204 | Current Problems in Cancer | 2017 | 7 Pages |
Abstract
With the use of high-throughput molecular profiling technologies, precision medicine trials are ongoing for adults with cancer. Similarly, there is an interest in how these techniques can be applied to tumors in children and adolescents to expand our understanding of the biology of pediatric cancers and evaluate the clinical implications of genomic testing for these patients. This article reviews the early studies in pediatric oncology showing the feasibility of this approach, describe the future plans to evaluate the clinical implications in a multicenter clinical trial and identify the challenges of applying genomics in this patient population.
Keywords
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Authors
Nita L. MD, Katherine MD, MSc, Carl E. MD, PhD, Susan N. MD, Yoon-Jae MD, Julia L. MD, AeRang MD, PhD, Theodore W. MD, Meredith S. MD, Naoko MD. PhD, James V. PhD, Donald Williams MD, PhD,