Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5665681 | Current Opinion in Immunology | 2017 | 8 Pages |
Abstract
â¢Eosinophilic esophagitis (EoE) is a tissue-specific disease.â¢EoE epithelium exhibits impaired barrier function and dysregulated differentiation.â¢Innate and adaptive immunologic mechanisms drive EoE pathogenesis.â¢Both genetic and environmental components influence EoE pathogenesis.â¢Recently developed rational EoE therapies reduce esophageal eosinophilia.
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Authors
Julie M Caldwell, Misu Paul, Marc E Rothenberg,