Article ID Journal Published Year Pages File Type
5665681 Current Opinion in Immunology 2017 8 Pages PDF
Abstract

•Eosinophilic esophagitis (EoE) is a tissue-specific disease.•EoE epithelium exhibits impaired barrier function and dysregulated differentiation.•Innate and adaptive immunologic mechanisms drive EoE pathogenesis.•Both genetic and environmental components influence EoE pathogenesis.•Recently developed rational EoE therapies reduce esophageal eosinophilia.

Related Topics
Life Sciences Immunology and Microbiology Immunology
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