| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5665962 | Diagnostic Microbiology and Infectious Disease | 2017 | 4 Pages |
â¢Resistance antibiotic genes advise a better therapeutic option to patients.â¢MDR is conferred by plasmids that can spread to different bacterial groups.â¢E. coli B2, ST131, CTX-M-15 producer is the most frequent pathogen causing UTI.â¢Sulfamethoxazole-trimethoprim as therapeutic option is no longer effective.
We investigated the molecular characteristics of ESBL-producing E. coli (ESBL-PEc) isolates from two hospitals and community settings in Ciudad Obregon, Sonora, Mexico. Between 2011 and 2014, thirty-seven ESBL-PEc isolates were collected. The major encoded ESBL was the blaCTX-M-15 gene (97%); followed by 13.5% of the blaSHV-12 gene, and 5.5% encoded the blaTLA-1 gene. The PMQR gene aac(6´)-Ib-cr was detected in 97% of the isolates and the qnrB gene, in one isolate. The ESBL-PEc isolates corresponded to phylogenetic group B2, ST131. Our results highlight the dissemination of ESBL-PEc isolates in northwest Mexico (Ciudad Obregon, Sonora).
