Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5669090 | Journal of Microbiology, Immunology and Infection | 2016 | 4 Pages |
Abstract
A 3-year-old boy with Mycoplasma pneumoniae infection associated with hemophagocytic lymphohistiocytosis (MP-HLH) presented with an elevated level of serum interleukin-12 (IL-12) and lower levels of interferon-γ and IL-10 compared to patients with Epstein-Barr virus infection associated with HLH (EBV-HLH). Unlike the patients with EBV-HLH, CD8+ CD5low HLA-DR++ T cells were not detected in our pediatric patient. Thus, the pathophysiology of MP-HLH may differ from that of EBV-HLH.
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Authors
Motoko Yasutomi, Shintaro Okazaki, Ikue Hata, Akihiko Tanizawa, Soichi Tamamura, Mikiko Kawakita, Yusei Ohshima,