Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5673103 | Journal of Virological Methods | 2017 | 5 Pages |
Abstract
Of the total 264 samples tested, 243 (92%) of samples were able to be amplified and sequenced to generate an integrase genotype. Sequencing results were similar between the testing laboratories with the exception of mixture detection. Mutations associated with integrase inhibitor resistance were observed in only 7% of integrase inhibitor naive samples, and some of these mutations are likely to be due to subtype-specific polymorphisms rather than selection by an integrase inhibitor.
Keywords
Related Topics
Life Sciences
Immunology and Microbiology
Virology
Authors
Carole L Wallis, Raquel V Viana, Shanmugam Saravanan, Carlos Silva de Jesus, Clement Zeh, Elias K Halvas, John W. Mellors,