| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5673407 | Microbes and Infection | 2017 | 10 Pages |
Abstract
Persistent stomach infection with Helicobacter pylori causes chronic mucosal inflammation (gastritis), which is widely recognized as an essential precursor to gastric cancer. The IL-1 interleukin family cytokines IL-1β and IL-18 have emerged as central mediators of mucosal inflammation. Here, we review the regulation and functions of these cytokines in H. pylori-induced inflammation and carcinogenesis.
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Authors
Le Son Tran, Michelle Chonwerawong, Richard L. Ferrero,