Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5674802 | Trends in Parasitology | 2017 | 4 Pages |
Abstract
Tick-induced allergy to red meat is associated with anti-α-Gal IgE antibody levels. We propose that tick salivary prostaglandin E2 triggers antibody class switching in mature B cells, increasing the levels of anti-α-Gal IgE antibodies. Immune tolerance to α-Gal in blood type B individuals might reduce the risk to this allergy.
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Immunology and Microbiology
Parasitology
Authors
Alejandro Cabezas-Cruz, Lourdes Mateos-Hernández, JindrÇch ChmelaÅ, Margarita Villar, José de la Fuente,