Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5676207 | American Journal of Obstetrics and Gynecology | 2017 | 15 Pages |
Abstract
Here we have provided an initial key insight into the interplay between neonatal establishment of the peripheral circadian clock in the liver and the ability of the gut microbiome to respond to dietary and metabolic stress. Because Npas2 expression in the liver is a target of maternal high-fat diet-induced metabolic perturbations during fetal development, we speculate that these findings have potential implications in the long-term metabolic health of their offspring.
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Authors
Derek S. PhD, Christopher J. PhD, Derrick M. BS, Danielle M. PhD, Pablo J. PhD, Cynthia D. MS, Kjersti M. MD, PhD,