Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5676490 | American Journal of Obstetrics and Gynecology | 2016 | 43 Pages |
Abstract
Increasing urge was associated with greater urgency incontinent participant than control activation of the interoceptive network and activation in networks that are determinants of self-awareness (default mode network) and of response to unexpected external stimuli (ventral attention network). Differences in connectivity between interoceptive networks and opposing attentional networks (ventral attention network vs dorsal attention network) were present even before bladder filling (in the resting state). These findings are strong evidence for a central nervous system component of urgency urinary incontinence that could be mediated by brain-directed therapies.
Related Topics
Health Sciences
Medicine and Dentistry
Medicine and Dentistry (General)
Authors
Loren H. MD, Yuko M. MD, Andrew B. MS, Rebecca G. MD, Josef M. BA, Andrew R. PhD,