Prevalence and predictors of hyperprolactinemia in subclinical hypothyroidism

Hyperprolactinemia is common in ScH, especially in those with TSH > 7.5 mIU/L. ROC analysis confirmed that TSH ≥ 7.51 mIU/L in females and ≥ 8.33 mIU/L in males had a sensitivity of ≈ 50% with a very high specificity of > 90% in detecting hyperprolactinemia. Prolactin screening may be warranted in ScH with TSH > 7.5mIU/L, and may form an indication for treating ScH.