Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5685792 | American Journal of Kidney Diseases | 2017 | 9 Pages |
Abstract
Acute kidney injury (AKI) is an increasingly common and feared complication in hospitalized patients. The selection of appropriate primary and secondary end points is critical to the design and eventual success of clinical trials aimed at preventing and treating AKI. In this article, we provide an overview of AKI definitions and suggestions on the rational selection of end points for clinical trials in various settings, including the prevention of contrast-induced AKI, prevention of cardiac surgeryâassociated AKI, treatment of established AKI, and treatment of dialysis-requiring AKI.
Keywords
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Authors
David E. MD, MMSc, Sushrut S. MD, MPH,