Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5686424 | The Journal of Urology | 2017 | 26 Pages |
Abstract
Using a robust and validated prognostic signature we found that a small but not insignificant proportion of histological Gleason 6 tumors harbored molecular characteristics of aggressive cancer. Molecular profiling of such tumors at diagnosis may better select patients for active surveillance at diagnosis and trigger appropriate intervention during followup.
Keywords
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Nephrology
Authors
Eric A. Klein, MarÃa Santiago-Jiménez, Kasra Yousefi, Bruce A. Robbins, Edward M. Schaeffer, Bruce J. Trock, Jeffrey Tosoian, Zaid Haddad, Seong Ra, R. Jeffrey Karnes, Robert B. Jenkins, John C. Cheville, Robert B. Den, Adam P. Dicker, Elai Davicioni,