| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5686771 | The Journal of Urology | 2017 | 26 Pages |
Abstract
Intermittent androgen deprivation therapy was associated with a lower risk of heart failure and fracture compared to continuous androgen deprivation therapy. This raises toxicity concerns for continuous relative to intermittent therapy and suggests that intermittent androgen deprivation therapy may represent a safer therapeutic choice in elderly men with advanced prostate cancer.
Keywords
ADTPSAGnRHRCTAmIPCAAndrogen antagonistsProstate specific antigenRiskADT, Androgen deprivation therapyProstate cancerSEERAcute myocardial infarctionAntineoplastic agentsProstatic neoplasmsheart failureSurveillance, Epidemiology and End ResultsGonadotropin-releasing hormoneHormonalRandomized Clinical Trial
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Authors
Huei-Ting Tsai, Ruth M. Pfeiffer, George K. Philips, Ana Barac, Alex Z. Fu, David F. Penson, Yingjun Zhou, Arnold L. Potosky,