| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5687292 | The Journal of Urology | 2016 | 28 Pages |
Abstract
To our knowledge this is the first study to demonstrate that PAXgene preserved whole blood can be used to obtain clinically relevant information regarding the expression of 2 AR-Vs. These data on a castration resistant prostate cancer cohort support a role for AR-Vs in resistance to therapies targeting the AR ligand-binding domain.
Keywords
mCRPCCRPCEpCAMCTCPSAProstate specific antigenAndrogenProtein isoformsTumorEMTBloodRadical prostatectomyMetastatic castration resistant prostate cancerCastration resistant prostate cancerepithelial cell adhesion moleculeProstatic neoplasmsBiomarkerspolymerase chain reactionPCRepithelial-to-mesenchymal transitioncirculating tumor cellReceptors
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Authors
Xichun Liu, Elisa Ledet, Dongying Li, Ary Dotiwala, Allie Steinberger, Allison Feibus, Jianzhuo Li, Yanfeng Qi, Jonathan Silberstein, Benjamin Lee, Yan Dong, Oliver Sartor, Haitao Zhang,