Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5688371 | Kidney International Reports | 2017 | 7 Pages |
Abstract
IntroductionIn hemodialysis patients on ferric citrate hydrate, the increase in ferritin level is mainly due to the administration of the compound. We investigated possible other factors associated with ferritin level and how erythropoietin resistance index and erythropoiesis in those patients were affected. We looked at ferritin-elevating factors using data from a Japanese phase III long-term clinical trial of ferric citrate hydrate.MethodsThe factors with a strong association with ferritin levels at week 28 were selected by the process of variable selection. In addition, selected factors were analyzed by Mixed Model for Repeated Measurement. Subjects were divided into 3 groups by quantiles (
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Authors
Keitaro Yokoyama, Masafumi Fukagawa, Takashi Akiba, Masaaki Nakayama, Toshiya Otoguro, Kana Yamada, Yasuo Nagamine, Steven Fishbane, Hideki Hirakata,