Predictive factors for the methotrexate treatment outcome in ectopic pregnancy: A comparative study of 400 cases

In this study, we showed that an initial hCG value <1000 IU/l and favorable early HCG kinetics were predictive factors for the successful medical treatment of ectopic pregnancy by methotrexate, and hematosalpinx and pretherapeutic blood progesterone >5 ng/ml at diagnosis were predictive of its failure. We also confirmed good tolerability for single-dose methotrexate protocols.