| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5690751 | Gynecologic Oncology | 2016 | 8 Pages |
Abstract
FOXA2 is frequently mutated in EEC. The pattern of FOXA2 mutations and expression in tumors suggests complex regulation and a haploinsufficient or dominant-negative tumor suppressor function. In vitro studies may shed light on how mutations in FOXA2 affect FOXA2 pioneer and/or transcription factor functions in EEC.
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Authors
B. Smith, R. Neff, D.E. Cohn, F.J. Backes, A.A. Suarez, D.G. Mutch, C.M. Rush, C.J. Walker, P.J. Goodfellow,