Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5691405 | European Journal of Obstetrics & Gynecology and Reproductive Biology | 2017 | 25 Pages |
Abstract
Aspirin has proven efficacy, but suboptimal adherence is widespread and difficult to accurately quantify. Little is currently known about aspirin adherence in pregnancy. RCTs evaluating aspirin effectiveness show over-reliance on qualitative adherence assessments vulnerable to inherent inaccuracies. Reliable adherence data is important to assess and optimise the clinical effectiveness of LDA. We propose that adherence should be formally assessed in future trials and that development of quantitative assessments may prove valuable for trial protocols.
Keywords
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Authors
Kate Navaratnam, Zarko Alfirevic, Munir Pirmohamed, Ana Alfirevic,