Article ID Journal Published Year Pages File Type
5693364 European Journal of Obstetrics & Gynecology and Reproductive Biology 2017 38 Pages PDF
Abstract
There was a reduction in vaginal tissue pentosidine in pregnancy with an associated increase in oestrogen receptor and glyoxalase I immunoexpression. Reduced glycation was associated with increased creeping of vaginal tissue. Oestrogen may therefore play a role in the increase of the vaginal wall's capacity to stretch through glyoxalase I up-regulation and subsequent glycation reduction. The new insight of the correlation of women's oestrogen level, glycation reaction and pelvic tissue mechanical property from this study may enhance our understanding of some pelvic organ diseases.
Related Topics
Health Sciences Medicine and Dentistry Obstetrics, Gynecology and Women's Health
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