| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5696381 | Journal of Reproductive Immunology | 2017 | 8 Pages |
Abstract
Our data demonstrate that preeclamptic sera produce toxic/dangerous micro- and nano-placental EVs which activated endothelial cells. This effect was reversed by antihypertensives. The increased levels of HMGB1 in EVs may contribute to endothelial cell activation.
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Authors
Xirong Xiao, Fengyi Xiao, Mingzhi Zhao, Mancy Tong, Michelle R. Wise, Peter R. Stone, Lawrence W. Chamley, Qi Chen,