Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5696769 | Reproductive BioMedicine Online | 2017 | 31 Pages |
Abstract
Consecutive subfertile couples with unexplained and mild male subfertility presenting in fertility clinics were asked to participate in a prospective cohort study. We constructed a multivariable prediction model with the predictors from the Hunault model and new potential predictors. The primary outcome, natural conception leading to an ongoing pregnancy, was observed in 1053 women of the 5184 included couples (20%). All predictors of the Hunault model were selected into the revised model plus an additional seven (woman's body mass index, cycle length, basal FSH levels, tubal status,history of previous pregnancies in the current relationship (ongoing pregnancies after natural conception, fertility treatment or miscarriages), semen volume, and semen morphology. Predictions from the revised model seem to concur better with observed pregnancy rates compared with the Hunault model; c-statistic of 0.71 (95% CI 0.69 to 0.73) compared with 0.59 (95% CI 0.57 to 0.61).
Related Topics
Health Sciences
Medicine and Dentistry
Obstetrics, Gynecology and Women's Health
Authors
Alexandra J. Bensdorp, Jan Willem van der Steeg, Pieternel Steures, J. Dik F. Habbema, Peter G.A. Hompes, Patrick M.M. Bossuyt, Fulco van der Veen, Ben W.J. Mol, Marinus J.C. Eijkemans,