Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5697521 | Cancer Treatment and Research Communications | 2017 | 6 Pages |
Abstract
We found no evidence for the activity of dovitinib in patients who had recently progressed on anti-VEGF therapy and toxicities were significant. In tumors progressing despite anti-VEGF therapy, a multitude of pro-angiogenic mediators are expressed, including members of the FGF pathway.
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Authors
Thomas J. Semrad, Edward J. Kim, Michael S. Tanaka, Jacob Sands, Chris Roberts, Rebekah A. Burich, Yu Li, David R. Gandara, Primo Jr., Philip C. Mack,