| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5697540 | Cancer Treatment and Research Communications | 2017 | 38 Pages |
Abstract
The significance of epithelio-mesenchymal transition in lung adenocarcinoma remains controversial in clinical settings. We retrospectively studied the combination of epithelial and mesenchymal markers on 256 patients. The EMT activation levels showed a trend for pathologic local invasiveness, node metastases, and poor survival. These findings suggest that EMT is the challenging target for the malignant progression, and is worth further investigation.
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Authors
Toshi Menju, Terumasa Sowa, Makoto Sonobe, Ryo Miyata, Koji Takahashi, Shigeto Nishikawa, Takao Nakanishi, Shinya Neri, Hiroyuki Cho, Masatsugu Hamaji, Kyoko Hijiya, Hideki Motoyama, Akihiro Aoyama, Toyofumi F. Chen-Yoshikawa, Toshihiko Sato,