| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5697623 | Cancer Treatment Reviews | 2017 | 34 Pages |
Abstract
Demethylating agents are able to improve clinical outcome and alter methylation status in patients with solid tumours. Although beneficial effect has been shown in individual patients, overall response is limited. Further research on biomarker predicting therapy efficacy is indicated, particularly in earlier stage and highly methylated tumours.
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Authors
J.F. Linnekamp, R. Butter, R. Spijker, J.P. Medema, H.W.M. van Laarhoven,