Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5699271 | Clinical Oncology | 2011 | 7 Pages |
Abstract
Single-agent carboplatin has modest activity in patients with recurrent HGG who have received at least two lines of chemotherapy. The overall time to progression is short and over two-thirds of patients had to discontinue treatment due to progressive disease. Among the small proportion of patients achieving stable disease or a partial response to treatment, the median survival is improved. More effective but well tolerated regimens are required for this patient population.
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Authors
L.J. Murray, C.H. Bridgewater, D. Levy,