Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5699549 | Clinical Oncology | 2008 | 8 Pages |
Abstract
The mitotic checkpoint genes, hsMAD2 and BubR1, were co-ordinately overexpressed in ESCC. Low hsMAD2 and BubR1 was associated with sensitivity to paclitaxel and docetaxel. Decreased hsMAD2 and BubR1 after radiochemotherapy may indicate the potential efficacy of taxanes as second-line chemotherapy for recurrent and metastatic oesophageal cancer.
Related Topics
Health Sciences
Medicine and Dentistry
Oncology
Authors
K. Tanaka, Y. Mohri, M. Ohi, T. Yokoe, Y. Koike, Y. Morimoto, C. Miki, H. Tonouchi, M. Kusunoki,