Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5699959 | Clinical Oncology | 2011 | 12 Pages |
Abstract
In this study, the greatest risk factors for the development of late toxicity 2 years after breast-conserving surgery and adjuvant radiotherapy were larger breast volume, baseline pre-radiotherapy surgical cosmesis, postoperative infection and possibly smoking. These factors seem to be more important than relatively small differences in dose inhomogeneity and the addition of boost radiotherapy at 2 years after the completion of radiotherapy. The modification of potentially preventable risk factors, such as postoperative infection and smoking, may limit the development of late toxicity after breast radiotherapy.
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Authors
G.C. Barnett, J.S. Wilkinson, A.M. Moody, C.B. Wilson, N. Twyman, G.C. Wishart, N.G. Burnet, C.E. Coles,