Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5700255 | Clinical Oncology | 2007 | 11 Pages |
Abstract
There was a dose-related reduction in rCBV and rCBF in normal brain after radiotherapy at higher dose levels. Although this study used a limited number of patients, it suggests that magnetic resonance perfusion imaging seems to act as a marker of subclinical response of normal brain and that there is an absence of an early hypersensitivity effect with small doses per fraction. Further studies are required with larger groups of patients to show that these results are statistically robust.
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Authors
S.J. Price, R. Jena, H.A.L. Green, N.F. Kirkby, A.G. Lynch, C.E. Coles, J.D. Pickard, J.H. Gillard, N.G. Burnet,