Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5701525 | Journal of Thoracic Oncology | 2017 | 27 Pages |
Abstract
Refined classification of LCLC has implications for diagnosis, prognostics, and therapy decisions. Our molecular analyses support the WHO 2015 classification of LCLC and LCNEC tumors, which herein follow different tumorigenic paths and can accordingly be stratified into different transcriptional subgroups, thus linking diagnostic immunohistochemical staining-driven classification with the transcriptional landscape of lung cancer.
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Authors
Anna MSc, Hans MD, PhD, Patrick MD, PhD, Srinivas PhD, Johanna PhD, Linnea MSc, Johan MD, PhD, Mats PhD, Christel MSc, Maria MD, PhD, Johan PhD,