Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5701526 | Journal of Thoracic Oncology | 2017 | 27 Pages |
Abstract
Here we have shown that an increase in a single cytokine, IL-17A, without additional mutations can promote lung cancer growth by promoting inflammation, which contributes to resistance to PD-1 blockade and sensitizes tumors to cytokine and neutrophil depletion.
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Authors
Esra A. PhD, Shohei MD, PhD, Yan PhD, Ruben PhD, Lauren E. BS, Michael BS, MD Maksudul PhD, Dillon M. MS, Robert BA, Masahisa MD, PhD, Meghana PhD, Julian PhD, Xiaoen MD, Tiquella BS, Jillian D. BS, Akio MD, Atsushi MD, PhD, Gordon J. PhD, Kwok-Kin MD,