Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5701789 | Journal of Thoracic Oncology | 2016 | 33 Pages |
Abstract
EGFR colocalization with GRB2 as assessed by PLA is not correlated with EGFR expression levels or mutation status, defining a patient group that may show EGFR pathway activation, as illustrated by its prognostic value. Future studies may determine whether this group is more likely to respond to EGFR-targeted therapies.
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Authors
Maria I. MD, Daniel E. MD, Mehmet MD, Joseph MD, Brian MD, Kurt A. MD, PhD, Konstantinos N. MD, PhD, David L. MD, PhD,