Article ID Journal Published Year Pages File Type
5702776 Urologic Oncology: Seminars and Original Investigations 2016 7 Pages PDF
Abstract
MLN2704 has limited activity in metastatic castration-resistant prostate cancer. Disulfide linker lability and rapid deconjugation lead to neurotoxicity and a narrow therapeutic window.
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Health Sciences Medicine and Dentistry Oncology
Preview
Phase 1/2 multiple ascending dose trial of the prostate-specific membrane antigen-targeted antibody drug conjugate MLN2704 in metastatic castration-resistant prostate cancer
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