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Comparison of the osteogenesis and fusion rates between activin A/BMP-2 chimera (AB204) and rhBMP-2 in a beagle's posterolateral lumbar spine model

Article ID Journal Published Year Pages File Type
5712716 The Spine Journal 2017 19 Pages PDF
Abstract
A low dose of AB204 with BCP as a carrier significantly promotes the fusion rate in a large animal model when compared with the rhBMP-2. These findings demonstrate that AB204 could be an alternative to rhBMP-2 to improve fusion rate.
Keywords
rhBMP-2OsteogenesisBeagle dogBiphasic calcium phosphatePosterolateral fusion
Related Topics
Health Sciences Medicine and Dentistry Orthopedics, Sports Medicine and Rehabilitation
Preview
Comparison of the osteogenesis and fusion rates between activin A/BMP-2 chimera (AB204) and rhBMP-2 in a beagle's posterolateral lumbar spine model
Authors
Guang Bin MD, PhD, Byung-Hak PhD, Jae Hyup MD, PhD,
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Journal
The Spine Journal
Journal: The Spine Journal
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