Article ID Journal Published Year Pages File Type
5713211 The Spine Journal 2016 20 Pages PDF
Abstract
Naringin effectively promotes the proliferation of degenerative human NP cells and improves the recuperation of the cells from degeneration by increasing expression of aggrecan, BMP-2, and Sox6 while inhibiting the expression of TNF-α and MMP3. This study suggests that naringin may represent an alternative therapeutic agent for disc degeneration.
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Health Sciences Medicine and Dentistry Orthopedics, Sports Medicine and Rehabilitation
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Therapeutic effects of naringin on degenerative human nucleus pulposus cells for discogenic low back pain
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