Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5713698 | American Journal of Otolaryngology | 2016 | 18 Pages |
Abstract
Data suggest that Type II congenital smell loss patients who exhibit both type I hyposmia and hypogeusia are genetically distinct from all other patients with Type II congenital smell loss. This distinction is based on decreased Fyb expression which correlated with abnormalities in two sensory modalities (hyposmia type I and hypogeusia). Only patients with these two specific sensory abnormalities expressed the Fyb antigen (encoded by the ACKR1 gene on the long arm of chromosome 1) at frequencies different from controls.
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Authors
William A. BA, Alexandra B. BA, Willy A. MD, Robert I. MD, PhD,