Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5715928 | Annals of Diagnostic Pathology | 2017 | 6 Pages |
Abstract
PD-1 seems to correlate with disease progression in epitheliotropic T cell dyscrasias ranging from minimal staining in prelymphomatous dyscrasias to significant staining in MF, likely reflecting the effects of PD-1 on inhibiting tumor surveillance regulatory T cell populations. PD-1 was consistently expressed in MF while it was consistently negative in primary CD30Â + LPD, suggesting the possibility of using PD-1 as a means of distinguishing CD30Â + MF from primary cutaneous ALCL.
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Authors
Giang Huong Nguyen, Luke C. Olson, Cynthia M. Magro,