Mini-symposium: pathology of non-neoplastic bone tumoursThe histology of metabolic bone disease

Patients with metabolic bone disease are usually cared for by endocrinologists. Pathologists may examine specimens if fragility fractures occur or if a bone biopsy is required. Some metabolic bone diseases have distinctive histologic features such as tunneling resorption in hyperparathyroidism, wide osteoid seams in osteomalacia, and bone marrow edema in transient osteoporosis. The histologic changes must always be correlated with clinical and radiographic features.