Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5719608 | The Journal of Pediatrics | 2017 | 4 Pages |
Abstract
In all surviving girls with Leigh syndrome, French Canadian variety, a mitochondrial disease, we detected premature ovarian failure, manifested as absent or arrested breast development, lack of menarche, high follicle-stimulating hormone, a prepubertal uterus, and small ovaries. Pubertal onset and progression should be evaluated in girls with mitochondrial diseases.
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Authors
Chiraz MD, PhD, Charles MD, Catherine MD, Grant A. MD, Guy MD, Céline MD, MSc,