Article ID Journal Published Year Pages File Type
57251 Catalysis Today 2009 7 Pages PDF
Abstract

A new insoluble polymer-bound bisoxazoline (IPB-box) was prepared by grafting a suitable chiral ligand derivative onto a commercial Merrifield resin. The material obtained by this route was employed in the asymmetric copper-catalyzed olefin cyclopropanation, obtaining good activity and enantioselectivity values (54–84% yield, 71–93% ee) for a range of substrates. In addition, some key factors required for the development of effective IPB-box systems are discussed, including the local ligand symmetry and the influence of immobilization technique and catalyst loading.

Related Topics
Physical Sciences and Engineering Chemical Engineering Catalysis
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