ReviewPET/MRI of the thorax, abdomen and retroperitoneum: Benefits of the breathing-synchronized scanning

•Hybrid imaging is essential in an oncologic diagnostic and therapy-response monitoring.•Benefits of PET/MRI in thorax, abdomen and retroperitoneum are not completely defined.•Breathing-synchronized PET scanning increases the detectability and improves assessment of lesions in thorax and abdomen.

Hybrid imaging using various radiopharmaceuticals is currently essential not only in detection and therapy response monitoring of tumors, but also in assessment of inflammatory or systemic diseases. Combination of positron emission tomography (PET) and magnetic resonance imaging (MRI) is still relatively new method with great prospects of comprehensive assessment using anatomical and multiple functional information. However, benefits of PET/MRI in thorax, abdomen and retroperitoneum are not completely defined. Breathing movements affect imaging of thoracic, abdominal and retroperitoneal organs and pathological structures using PET and MRI. Fast MRI sequences are performed using breath-hold technique; however, acquisition of longer sequences and PET scanning need to be breathing-synchronized. Review article summarizes concrete PET/MRI protocols and importance of concrete MRI sequences and radiopharmaceuticals in different pathological lesions with focus on benefit of breathing-synchronized techniques.